diCOMBINE - image point-annotation software

diCOMBINE is a 3D DICOM visualization and point annotation app.

It allows doctors to review patients’ CT images and pinpoint the bone metastasis centers and label the metastasis type. diCOMBINE provide panning, zooming, and window/level adjusting options.

Publications describing this code include:

• Hossein Naseri, Sonia Skamene, Marwan Tolba, Mame Daro Faye, Paul Ramia, Julia Khriguian, Haley M. Patrick, Axia X. Andrade Hernandez, Marc David, John Kildea (2022). Radiomics-based machine learning models to distinguish between metastatic and healthy bone using lesion-center-based geometric regions of interest. In Nature Scientific Reports.